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Ry. Early limited exposure to NDEA had no significant effect on any of the indices measured relative to control. Chronic HFD feeding significantly increased the mean levels of pGSK-3b, GFAP, and N-Tyr relative to all other groups (P
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Affected in AD, as well as other neurodegenerative diseases [47,50, 53,56,59,60,65,68,69,71], and cerebellar degeneration causes cognitive impairment [49,57-59,62,63,66,67,72]. Previous studies demonstrated significant structural, functional, and metabolic abnormalities in AD cerebella [57-59,82], including insulin and IGF resistance [30],similar to the findings in more traditional targets of AD,
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N water bath for 4 h at 55 . The sample was filtered and extracted again with 200 ml of 20 ethanol. Then by keeping it in water bath for some time, the volume dropped down to 40 ml. The sample was then transferred into a separating funnel and added 20 ml diethyl ether to it with vigorous shaking. Both the diethyl ether and aqueous layers were separated. The aqueous layer was mixed with 60 ml of n
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R protein; AbPP-Ab: amyloid-b peptide; AChE: acetylcholinesterase; AD: Alzheimer's disease; CER: Ceramide synthase; ChAT: choline acetyltransferase; ELISA: enzyme-linked immunosorbant assay; GFAP: glial fibrillary acidic protein; GSK-3b: glycogen synthase kinase-3b; H E: hematoxylin and eosin; HFD: high fat diet; HNE: 4-hydroxy-2-nonenal; HRP: horseradish peroxidase; i.p.: intraperitoneal; IGF: In
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R protein; AbPP-Ab: amyloid-b peptide; AChE: acetylcholinesterase; AD: Alzheimer's disease; CER: Ceramide synthase; ChAT: choline acetyltransferase; ELISA: enzyme-linked immunosorbant assay; GFAP: glial fibrillary acidic protein; GSK-3b: glycogen synthase kinase-3b; H E: hematoxylin and eosin; HFD: high fat diet; HNE: 4-hydroxy-2-nonenal; HRP: horseradish peroxidase; i.p.: intraperitoneal; IGF: In
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N expectedly cannot speak freely. To our knowledge, this study is the first survey in Erbil city to assess the past year IPV. Prevalence of past year IPV in this study (45.3 ) is similar to those reported in Baghdad (44 ) [14], and in Omdurman, Sudan (41.6 ) [26]. However, it is lower than that reported in Madina, Saudi Arabia (58.7 ) [12] and higher than that reported in China 26 [20] and Esfaha
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N expectedly cannot speak freely. To our knowledge, this study is the first survey in Erbil city to assess the past year IPV. Prevalence of past year IPV in this study (45.3 ) is similar to those reported in Baghdad (44 ) [14], and in Omdurman, Sudan (41.6 ) [26]. However, it is lower than that reported in Madina, Saudi Arabia (58.7 ) [12] and higher than that reported in China 26 [20] and Esfaha
1
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